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Hibernating Myocardium Information

In cardiology, hibernating myocardium is a state when some segments of the myocardium exhibit abnormalities of contractile function.[1] These abnormalities can be visualised during echocardiography or ventriculography. The finding of a perfusion or metabolic mismatch between PET-FDG and PET-NH3 is indicative of decreased metabolism. The wall of the affected segments is hypo-, a-, or dyskinetic.

The phenomenon is highly significant clinically because it usually manifests itself in the setting of chronic ischemia, that is potentially reversible by revascularisation via cardiac catheterization. The regions of myocardium are still viable and can restore its function. There develops a new steady state between myocardial blood flow (MBF) and myocardial function, MBF reduced and in consequence function is reduced too. The clinical situations where one can expect hibernating myocardium are:

See also

References

  1. ^ Wijns W, Vatner SF, Camici PG (July 1998). "Hibernating myocardium". N. Engl. J. Med. 339 (3): 173–81. doi:10.1056/NEJM199807163390307. PMID 9664095. http://content.nejm.org/cgi/pmidlookup?view=short&pmid=9664095&promo=ONFLNS19.
Cardiovascular disease: heart disease · Circulatory system pathology (I00–I52, 390–429)
Ischaemic
CD/CHD CAD · Coronary thrombosis · Coronary vasospasm · Coronary artery aneurysm · Coronary artery dissection · Myocardial Bridge
Active ischemia Angina pectoris (Prinzmetal's angina, Stable angina) · Acute coronary (Unstable angina, Myocardial infarction / heart attack)
Sequelae hours (Myocardial stunning, Hibernating myocardium) · days (Myocardial rupture) · weeks (Aneurysm of heart/Ventricular aneurysm, Dressler's syndrome)
Layers
Pericardium Pericarditis (Acute, Chronic/Constrictive) · Pericardial effusion (Hemopericardium, Cardiac tamponade)
Myocardium Myocarditis (Chagas disease) Cardiomyopathy: Dilated (Alcoholic) · Hypertrophic · Restrictive (Loeffler endocarditis, Cardiac amyloidosis, Endocardial fibroelastosis) Arrhythmogenic right ventricular dysplasia
Endocardium/ valves
Endocarditis Infective endocarditis (Subacute bacterial endocarditis) · noninfective endocarditis (Nonbacterial thrombotic endocarditis, Libman-Sacks endocarditis)
Valves mitral (regurgitation, prolapse, stenosis) · aortic (stenosis, insufficiency) · tricuspid (stenosis, insufficiency) · pulmonary (stenosis, insufficiency)
Conduction/ arrhythmia
Bradycardia Sinus bradycardia · Sick sinus syndrome Heart block: Sinoatrial · AV (, , ) · Intraventricular (Bundle branch/Right/Left, Left anterior fascicular/Left posterior fascicular, Bifascicular/Trifascicular) · Adams–Stokes syndrome
Tachycardia (paroxysmal and sinus)
Supraventricular Atrial (Multifocal) · Junctional (AV nodal reentrant, Junctional ectopic)
Ventricular Torsades de pointes · Catecholaminergic polymorphic · Accelerated idioventricular rhythm
Premature contraction Atrial · Ventricular
Pre-excitation syndrome Wolff-Parkinson-White · Lown-Ganong-Levine
Flutter/fibrillation Atrial flutter · Ventricular flutter · Atrial fibrillation (Familial) · Ventricular fibrillation
Pacemaker Wandering pacemaker · Ectopic pacemaker/Ectopic beat · Parasystole · Multifocal atrial tachycardia · Pacemaker syndrome
Long QT syndrome Romano-Ward syndrome · Andersen-Tawil syndrome · Jervell and Lange-Nielsen syndrome
Cardiac arrest Sudden cardiac death · Asystole · Pulseless electrical activity · Sinoatrial arrest
Other/ungrouped hexaxial reference system (Right axis deviation, Left axis deviation) · QT (Short QT syndrome) · T (T wave alternans) · ST (Osborn wave, ST elevation, ST depression)
Cardiomegaly Ventricular hypertrophy (Left, Right/Cor pulmonale) · Atrial enlargement (Left, Right)
Other Cardiac fibrosis · Heart failure (Diastolic heart failure, Cardiac asthma) · Rheumatic fever

: HRT

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